Scientists from Institute of Nano Science and Technology (INST) Mohali, an autonomous institute of Department of Science and Technology, used Dopamine Receptor D3 (DRD3) conjugated to 17β-Estradiol-loaded chitosan nanoparticles that led to sustained release of 17β-Estradiol (E2) to the brain. 

Initial studies indicate that this nano-formulation not only improves the pharmacokinetics of existing treatment options but also opens avenues for the development of new therapeutics targeting the underlying pathophysiological mechanisms of Parkinson’s disease. The ability to adjust the size, shape, and surface properties of nanoparticles allows for a customizable approach, catering to the specific needs of individual patients.

In conclusion, the advent of new nano-formulations represents a significant leap forward in the quest for safer and more effective treatments for Parkinson’s disease. By leveraging the capabilities of nanotechnology, researchers are poised to revolutionize the therapeutic landscape, ultimately improving the quality of life for millions affected by this challenging condition. Continued research and clinical trials will be essential to validate these promising findings and translate them into standard clinical practice, marking a hopeful future for Parkinson’s patients.

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